The_Scientist_September_2012.pdf

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SEPTEMBER 2012 | WWW.THE-SCIENTIST.COM
THE STAR-NOSED
MOLE’S AMAZING
TACTILE ORGAN
THE UNIQUE
RESPONSE TO
GENTLE TOUCH
PROSTHETICS
THAT CAN FEEL
PLUS
ALTERED TOUCH
PERCEPTION IN
DEAF PEOPLE
MAKING
SENSE OF
TOUCH
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60% GC
bp
4900
2900
1900
1100
700
500
300
L
A
B
C
D
A
B
78% GC
C
D
Amplification of two human genomic amplicons of mid to high GC content.
All reactions were conducted using 30 cycles of amplification and visualized
by microfluidic LabChip
®
analysis. All polymerases were cycled according to
manufacturer’s recommendations. For the 78% GC amplicon, GC Buffers or
enhancers were used when supplied with the polymerase.
A = Q5
™
High-Fidelity DNA Polymerase (NEB)
B = Phusion
®
High-Fidelity DNA Polymerase (NEB)
C = KOD DNA Polymerase (EMD)
D = PfuUltra
™
High-Fidelity DNA Polymerase (Agilent)
PHUSION
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is a registered trademark and property of Thermo Fisher Scientific.
Phusion
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DNA Polymerase was developed by Finnzymes Oy, now a part of Thermo Fisher Scientific.
PFUULTRA
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is a trademark of Agilent Technologies, Inc.
LABCHIP
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is a registered trademark of Caliper Life Sciences, part of Perkin Elmer, Inc.
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is a trademark of New England Biolabs, Inc.
SEPTEMBER 2012
Contents
THE SCIENTIST
WWW.THE-SCIENTIST.COM
VOLUME 26 NUMBER 09
COURTESY OF KENNETH CATANIA; © PM IMAGES; COURTESY OF JOHNS HOPKINS UNIVERSITY APPLIED PHYSICS LABORATORY
Features
ON THE COVER: © LUCA PIERRO PHOTOGRAPHY
28
A Nose for Touch
The remarkable ability
of the star-nosed mole to interpret
its surroundings through touch
is yielding clues about mammalian
sensory processing in general.
BY KENNETH C. CATANIA
34
Pleasant to the Touch
Scientists hope an understanding
of nerve fibers responsive only
to pleasant touch will give insight
into the role the sense plays
in social bonding.
BY SABRINA RICHARDS
40
Missing Touch
Bionic fingers. Rewired nerves.
Science fiction becomes reality as
scientists attempt to give prosthetics
a sense of touch.
BY MEGAN SCUDELLARI
09.2012 | THE SCIENTIST
3

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