(Topics in Medicinal Chemistry) James R. Empfield, Michael P Clark-Reducing Drug Attrition-Springer (2015).pdf

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Topics in Medicinal Chemistry 11
James R. Empfield
Michael P. Clark
Editors
Reducing
Drug
Attrition
11
Topics in Medicinal Chemistry
Editorial Board:
P. R. Bernstein, Rose Valley, USA
A. Buschauer, Regensburg, Germany
G. I. Georg, Minneapolis, USA
J. A. Lowe, Stonington, USA
U. Stilz, Malov, Denmark
C. T. Supuran, Sesto Fiorentino (Firenze), Italy
A. K. Saxena, Lucknow, India
Aims and Scope
Drug research requires interdisciplinary team-work at the interface between chemis-
try, biology and medicine. Therefore, the new topic-related series
Topics in Medicinal
Chemistry
will cover all relevant aspects of drug research, e.g. pathobiochemistry
of diseases, identification and validation of (emerging) drug targets, structural
biology, drugability of targets, drug design approaches, chemogenomics, synthet-
ic chemistry including combinatorial methods, bioorganic chemistry, natural
compounds, high-throughput screening, pharmacological in vitro and in vivo
investigations, drug-receptor interactions on the molecular level, structure-activ-
ity relationships, drug absorption, distribution, metabolism, elimination, toxicol-
ogy and pharmacogenomics.
In general, special volumes are edited by well known guest editors.
In references
Topics in Medicinal Chemistry
is abbreviated
Top Med Chem
and is
cited as a journal.
More information about this series at
http://www.springer.com/series/7355
James R. Empfield Michael P. Clark
l
Editors
Reducing Drug Attrition
With contributions by
C.G. Jackson
Á
A.S. Kalgutkar
Á
A.N.R. Nedderman
Á
P. Siegl
Á
D.K. Spracklin
Á
K.W. Ward
Editors
James R. Empfield
Vertex Pharmaceuticals
Boston
Massachusetts
USA
Michael P. Clark
Vertex Pharmaceuticals
Boston
Massachusetts
USA
ISSN 1862-2461
ISSN 1862-247X (electronic)
ISBN 978-3-662-43913-5
ISBN 978-3-662-43914-2 (eBook)
DOI 10.1007/978-3-662-43914-2
Springer Heidelberg New York Dordrecht London
Library of Congress Control Number: 2014956013
#
Springer-Verlag Berlin Heidelberg 2014
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